A Novel Dual Fluorochrome Near-Infrared Imaging Probe for Potential Alzheimer’s Enzyme Biomarkers-BACE1 and Cathepsin D
A molecular imaging probe to fluorescently image the β-site of the amyloid precursor protein (APP) cleaving enzyme 1 (BACE1) and cathepsin D (CatD) enzymes associated with Alzheimer’s disease (AD) was designed and synthesized. This imaging probe was built upon iron oxide nanoparti...
Main Authors: | Jenny M. Tam, Lee Josephson, Alexander R. Pilozzi, Xudong Huang |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-01-01
|
Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/25/2/274 |
Similar Items
-
Simultaneous Monitoring of Multi-Enzyme Activity and Concentration in Tumor Using a Triply Labeled Fluorescent In Vivo Imaging Probe
by: Jenny Tam, et al.
Published: (2020-04-01) -
A Simple Near‐Infrared Fluorescent Probe for the Detection of Peroxynitrite
by: Luling Wu, et al.
Published: (2019-12-01) -
A near-infrared fluorescent probe for selective detection of fluorion
by: Kang Yan-Fei, et al.
Published: (2020-03-01) -
A Review of Small Molecule Inhibitors and Functional Probes of Human Cathepsin L
by: Dibyendu Dana, et al.
Published: (2020-02-01) -
Imaging Dynamic Peroxynitrite Fluxes in Epileptic Brains with a Near‐Infrared Fluorescent Probe
by: Jiong‐sheng Hu, et al.
Published: (2019-08-01)