A novel vitamin B9 sensor based on modified screen-printed electrode

• Main Authors: Hamid Sarhadi, Zare Maryam
• Format: Article
• Language: English
• Published: International Association of Physical Chemists (IAPC) 2020-10-01
• Series: Journal of Electrochemical Science and Engineering
• Subjects: Voltammetric sensor; ZnFe2O4 magnetic nanoparticles; modified electrode; folic acid
• Online Access: https://www.pub.iapchem.org/ojs/index.php/JESE/article/view/878

In the field of determination of vitamin B9 (folic acid, FA), we have described the development of a sensitive electrochemical sensor through promoting the screen-printed electrode (SPE) and taking the advantage of zinc ferrite magnetic nanoparticles (ZnFe2O4MNPs). Cyclic voltammetry (CV) experiments demonstrated the powerful activity of ZnFe2O4MNPs/SPE for electrooxidation of FA by showing the prominent oxidation peak at 600 mV vs. Ag/AgCl. By differential pulse voltammetry (DPV) measurements, a linear relation between current response and concentration of vitamin B9 was determined in the range of 1.0–100.0 µM, and detection limit is found to be 0.3 µM (S/N=3). Except high sensitivity, the developed sensor demonstrated high stability, reproducibility and repeatability, and was also successfully applied to specify FA in real samples of vitamin B9 tablets and human urine.