Macrophage Migration Inhibitory Factor (MIF) Prevents Maternal Death, but Contributes to Poor Fetal Outcome During Congenital Toxoplasmosis

Macrophage Migration Inhibitory Factor (MIF) Prevents Maternal Death, but Contributes to Poor Fetal Outcome During Congenital Toxoplasmosis

Migration inhibitory factor (MIF) is a pro-inflammatory cytokine that plays important roles in physiology, pathology, immunology and parasitology, including the control of infection by protozoa parasites such as Toxoplasma gondii. As the MIF function in congenital toxoplasmosis is not fully elucidat...

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Bibliographic Details
Main Authors: Angelica O. Gomes, Bellisa F. Barbosa, Priscila S. Franco, Mayara Ribeiro, Rafaela J. Silva, Paula S. G. Gois, Karine C. Almeida, Mariana B. Angeloni, Andressa S. Castro, Pâmela M. Guirelli, João V. Cândido, Javier E. L. Chica, Neide M. Silva, Tiago W. P. Mineo, José R. Mineo, Eloisa A. V. Ferro
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Microbiology
Subjects:
Toxoplasma gondii
maternal-fetal interface
MIF
CD74
IDO
immune response
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2018.00906/full

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