Developmental context determines latency of MYC-induced tumorigenesis.

Developmental context determines latency of MYC-induced tumorigenesis.

One of the enigmas in tumor biology is that different types of cancers are prevalent in different age groups. One possible explanation is that the ability of a specific oncogene to cause tumorigenesis in a particular cell type depends on epigenetic parameters such as the developmental context. To ad...

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Bibliographic Details
Main Authors: Shelly Beer, Anders Zetterberg, Rebecca A Ihrie, Ryan A McTaggart, Qiwei Yang, Nicole Bradon, Constadina Arvanitis, Laura D Attardi, Sandy Feng, Boris Ruebner, Robert D Cardiff, Dean W Felsher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2004-11-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC519000?pdf=render

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http://europepmc.org/articles/PMC519000?pdf=render

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