Diaphragmatic Neurophysiology and Respiratory Markers in ALS

Diaphragmatic Neurophysiology and Respiratory Markers in ALS

The main reason for short survival in amyotrophic lateral sclerosis (ALS) is involvement of respiratory muscles. Severe compromise of diaphragmatic function due to marked loss of motor units causes poor inspiratory strength leading to symptomatic respiratory fatigue, and hypercapnia and hypoxemia, o...

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Bibliographic Details
Main Authors: Mamede de Carvalho, Michael Swash, Susana Pinto
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Neurology
Subjects:
amyotrophic lateral sclerosis
diaphragm physiology
progression
respiratory function tests
survival
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.00143/full

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