Total sleep deprivation increases pain sensitivity, impairs conditioned pain modulation and facilitates temporal summation of pain in healthy participants.

Chronic pain patients often suffer from insomnia or impaired sleep which has been associated with increased pain sensitivity, but a limited amount of studies have investigated the effects of total sleep deprivation on central pain mechanisms. Therefore, the aim of this study was to determine the eff...

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Bibliographic Details
Main Authors: Alexander Torp Staffe, Mathias Winther Bech, Sara Louise Kjær Clemmensen, Henriette Tranberg Nielsen, Dennis Boye Larsen, Kristian Kjær Petersen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0225849