The Left and Right Ventricles Respond Differently to Variation of Pacing Delays in Cardiac Resynchronization Therapy: A Combined Experimental- Computational Approach

The Left and Right Ventricles Respond Differently to Variation of Pacing Delays in Cardiac Resynchronization Therapy: A Combined Experimental- Computational Approach

Introduction: Timing of atrial, right (RV), and left ventricular (LV) stimulation in cardiac resynchronization therapy (CRT) is known to affect electrical activation and pump function of the LV. In this study, we used computer simulations, with input from animal experiments, to investigate the effec...

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Bibliographic Details
Main Authors: Erik Willemen, Rick Schreurs, Peter R. Huntjens, Marc Strik, Gernot Plank, Edward Vigmond, John Walmsley, Kevin Vernooy, Tammo Delhaas, Frits W. Prinzen, Joost Lumens
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Physiology
Subjects:
cardiac resynchronization therapy
right ventricle
optimization
computer simulation
therapy optimization studies
CircAdapt
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00017/full

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