(8S,9R,10S,11S,13S,14S,16S,17R)-4,4-Dichloro-16β-methyl-3,20-dioxo-17,21-bis(propanoyloxy)-5β,8β-epoxypregna-1,9-diene

(8S,9R,10S,11S,13S,14S,16S,17R)-4,4-Dichloro-16β-methyl-3,20-dioxo-17,21-bis(propanoyloxy)-5β,8β-epoxypregna-1,9-diene

The title compound, C28H34Cl2O7, is a derivative of the glucocorticoid steroid beclomethasone dipropionate. It features an expoxide linkage [angle at oxygen = 96.6 (2)°]. The dichlorocyclohexenone ring adopts an envelope conformation, with the C atom bearing the two Cl sub...

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Main Authors: Kamal Aziz Ketuly, A. Hamid A. Hadi, Seik Weng Ng
Format: Article
Language:English
Published: International Union of Crystallography 2009-09-01
Series:Acta Crystallographica Section E
Online Access:http://scripts.iucr.org/cgi-bin/paper?S1600536809028293
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spelling doaj-d9e85675661e427ab04ace248abde7e82020-11-25T01:52:39ZengInternational Union of CrystallographyActa Crystallographica Section E1600-53682009-09-01659o2220o222010.1107/S1600536809028293(8S,9R,10S,11S,13S,14S,16S,17R)-4,4-Dichloro-16β-methyl-3,20-dioxo-17,21-bis(propanoyloxy)-5β,8β-epoxypregna-1,9-dieneKamal Aziz KetulyA. Hamid A. HadiSeik Weng NgThe title compound, C28H34Cl2O7, is a derivative of the glucocorticoid steroid beclomethasone dipropionate. It features an expoxide linkage [angle at oxygen = 96.6 (2)°]. The dichlorocyclohexenone ring adopts an envelope conformation, with the C atom bearing the two Cl substituents representing the flap. The dichloromethyl C atom deviates by 0.471 (4) Å from the plane defined by the other five atoms, whose maximum r.m.s. deviation is 0.04 Å. http://scripts.iucr.org/cgi-bin/paper?S1600536809028293
collection DOAJ
language English
format Article
sources DOAJ
author Kamal Aziz Ketuly
A. Hamid A. Hadi
Seik Weng Ng
spellingShingle Kamal Aziz Ketuly
A. Hamid A. Hadi
Seik Weng Ng
(8S,9R,10S,11S,13S,14S,16S,17R)-4,4-Dichloro-16β-methyl-3,20-dioxo-17,21-bis(propanoyloxy)-5β,8β-epoxypregna-1,9-diene
Acta Crystallographica Section E
author_facet Kamal Aziz Ketuly
A. Hamid A. Hadi
Seik Weng Ng
author_sort Kamal Aziz Ketuly
title (8S,9R,10S,11S,13S,14S,16S,17R)-4,4-Dichloro-16β-methyl-3,20-dioxo-17,21-bis(propanoyloxy)-5β,8β-epoxypregna-1,9-diene
title_short (8S,9R,10S,11S,13S,14S,16S,17R)-4,4-Dichloro-16β-methyl-3,20-dioxo-17,21-bis(propanoyloxy)-5β,8β-epoxypregna-1,9-diene
title_full (8S,9R,10S,11S,13S,14S,16S,17R)-4,4-Dichloro-16β-methyl-3,20-dioxo-17,21-bis(propanoyloxy)-5β,8β-epoxypregna-1,9-diene
title_fullStr (8S,9R,10S,11S,13S,14S,16S,17R)-4,4-Dichloro-16β-methyl-3,20-dioxo-17,21-bis(propanoyloxy)-5β,8β-epoxypregna-1,9-diene
title_full_unstemmed (8S,9R,10S,11S,13S,14S,16S,17R)-4,4-Dichloro-16β-methyl-3,20-dioxo-17,21-bis(propanoyloxy)-5β,8β-epoxypregna-1,9-diene
title_sort (8s,9r,10s,11s,13s,14s,16s,17r)-4,4-dichloro-16β-methyl-3,20-dioxo-17,21-bis(propanoyloxy)-5β,8β-epoxypregna-1,9-diene
publisher International Union of Crystallography
series Acta Crystallographica Section E
issn 1600-5368
publishDate 2009-09-01
description The title compound, C28H34Cl2O7, is a derivative of the glucocorticoid steroid beclomethasone dipropionate. It features an expoxide linkage [angle at oxygen = 96.6 (2)°]. The dichlorocyclohexenone ring adopts an envelope conformation, with the C atom bearing the two Cl substituents representing the flap. The dichloromethyl C atom deviates by 0.471 (4) Å from the plane defined by the other five atoms, whose maximum r.m.s. deviation is 0.04 Å.
url http://scripts.iucr.org/cgi-bin/paper?S1600536809028293
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AT ahamidahadi 8s9r10s11s13s14s16s17r44dichloro16amp946methyl320dioxo1721bispropanoyloxy5amp9468amp946epoxypregna19diene
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