Hemorrhagic choroidal melanoma
Purpose: To demonstrate the clinical pathologic correlation in a hemorrhagic choroidal melanoma. Observations: A 52 year old patient presented with a large choroidal mass associated with vitreous and retinal hemorrhage. The eye was enucleated and histopathology demonstrated epithelioid-type MART1 po...
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2018-06-01
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Series: | American Journal of Ophthalmology Case Reports |
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doaj-d9db6344fd41437db3131108811ee62b2020-11-24T23:18:48ZengElsevierAmerican Journal of Ophthalmology Case Reports2451-99362018-06-0110105107Hemorrhagic choroidal melanomaPatrick Oellers0Natalie Wolkow1Frederick A. Jakobiec2Ivana K. Kim3Retina Service, Department of Ophthalmology, Mass Eye and Ear, Harvard Medical School, Boston, MA, USADavid G. Cogan Laboratory of Ophthalmic Pathology, Department of Ophthalmology, Mass Eye and Ear, Boston, MA, USADavid G. Cogan Laboratory of Ophthalmic Pathology, Department of Ophthalmology, Mass Eye and Ear, Boston, MA, USARetina Service, Department of Ophthalmology, Mass Eye and Ear, Harvard Medical School, Boston, MA, USA; Corresponding author.Purpose: To demonstrate the clinical pathologic correlation in a hemorrhagic choroidal melanoma. Observations: A 52 year old patient presented with a large choroidal mass associated with vitreous and retinal hemorrhage. The eye was enucleated and histopathology demonstrated epithelioid-type MART1 positive tumor cells consistent with choroidal melanoma. The tumor had broken through Bruch's membrane, which led to localized vascular compression with bleeding into the subretinal space, retina and vitreous. Conclusions and importance: Choroidal melanoma rarely presents with hemorrhage. Tumor rupture through Bruch's membrane may result in a tourniquet effect on the tumor vasculature leading to massive hemorrhage, as in this case. A high level of clinical suspicion is required to make the diagnosis. Keywords: Choroidal melanoma, Hemorrhagic melanomahttp://www.sciencedirect.com/science/article/pii/S2451993617303389 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Patrick Oellers Natalie Wolkow Frederick A. Jakobiec Ivana K. Kim |
spellingShingle |
Patrick Oellers Natalie Wolkow Frederick A. Jakobiec Ivana K. Kim Hemorrhagic choroidal melanoma American Journal of Ophthalmology Case Reports |
author_facet |
Patrick Oellers Natalie Wolkow Frederick A. Jakobiec Ivana K. Kim |
author_sort |
Patrick Oellers |
title |
Hemorrhagic choroidal melanoma |
title_short |
Hemorrhagic choroidal melanoma |
title_full |
Hemorrhagic choroidal melanoma |
title_fullStr |
Hemorrhagic choroidal melanoma |
title_full_unstemmed |
Hemorrhagic choroidal melanoma |
title_sort |
hemorrhagic choroidal melanoma |
publisher |
Elsevier |
series |
American Journal of Ophthalmology Case Reports |
issn |
2451-9936 |
publishDate |
2018-06-01 |
description |
Purpose: To demonstrate the clinical pathologic correlation in a hemorrhagic choroidal melanoma. Observations: A 52 year old patient presented with a large choroidal mass associated with vitreous and retinal hemorrhage. The eye was enucleated and histopathology demonstrated epithelioid-type MART1 positive tumor cells consistent with choroidal melanoma. The tumor had broken through Bruch's membrane, which led to localized vascular compression with bleeding into the subretinal space, retina and vitreous. Conclusions and importance: Choroidal melanoma rarely presents with hemorrhage. Tumor rupture through Bruch's membrane may result in a tourniquet effect on the tumor vasculature leading to massive hemorrhage, as in this case. A high level of clinical suspicion is required to make the diagnosis. Keywords: Choroidal melanoma, Hemorrhagic melanoma |
url |
http://www.sciencedirect.com/science/article/pii/S2451993617303389 |
work_keys_str_mv |
AT patrickoellers hemorrhagicchoroidalmelanoma AT nataliewolkow hemorrhagicchoroidalmelanoma AT frederickajakobiec hemorrhagicchoroidalmelanoma AT ivanakkim hemorrhagicchoroidalmelanoma |
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1725580004801118208 |