Hemorrhagic choroidal melanoma

Purpose: To demonstrate the clinical pathologic correlation in a hemorrhagic choroidal melanoma. Observations: A 52 year old patient presented with a large choroidal mass associated with vitreous and retinal hemorrhage. The eye was enucleated and histopathology demonstrated epithelioid-type MART1 po...

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Main Authors: Patrick Oellers, Natalie Wolkow, Frederick A. Jakobiec, Ivana K. Kim
Format: Article
Language:English
Published: Elsevier 2018-06-01
Series:American Journal of Ophthalmology Case Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2451993617303389
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spelling doaj-d9db6344fd41437db3131108811ee62b2020-11-24T23:18:48ZengElsevierAmerican Journal of Ophthalmology Case Reports2451-99362018-06-0110105107Hemorrhagic choroidal melanomaPatrick Oellers0Natalie Wolkow1Frederick A. Jakobiec2Ivana K. Kim3Retina Service, Department of Ophthalmology, Mass Eye and Ear, Harvard Medical School, Boston, MA, USADavid G. Cogan Laboratory of Ophthalmic Pathology, Department of Ophthalmology, Mass Eye and Ear, Boston, MA, USADavid G. Cogan Laboratory of Ophthalmic Pathology, Department of Ophthalmology, Mass Eye and Ear, Boston, MA, USARetina Service, Department of Ophthalmology, Mass Eye and Ear, Harvard Medical School, Boston, MA, USA; Corresponding author.Purpose: To demonstrate the clinical pathologic correlation in a hemorrhagic choroidal melanoma. Observations: A 52 year old patient presented with a large choroidal mass associated with vitreous and retinal hemorrhage. The eye was enucleated and histopathology demonstrated epithelioid-type MART1 positive tumor cells consistent with choroidal melanoma. The tumor had broken through Bruch's membrane, which led to localized vascular compression with bleeding into the subretinal space, retina and vitreous. Conclusions and importance: Choroidal melanoma rarely presents with hemorrhage. Tumor rupture through Bruch's membrane may result in a tourniquet effect on the tumor vasculature leading to massive hemorrhage, as in this case. A high level of clinical suspicion is required to make the diagnosis. Keywords: Choroidal melanoma, Hemorrhagic melanomahttp://www.sciencedirect.com/science/article/pii/S2451993617303389
collection DOAJ
language English
format Article
sources DOAJ
author Patrick Oellers
Natalie Wolkow
Frederick A. Jakobiec
Ivana K. Kim
spellingShingle Patrick Oellers
Natalie Wolkow
Frederick A. Jakobiec
Ivana K. Kim
Hemorrhagic choroidal melanoma
American Journal of Ophthalmology Case Reports
author_facet Patrick Oellers
Natalie Wolkow
Frederick A. Jakobiec
Ivana K. Kim
author_sort Patrick Oellers
title Hemorrhagic choroidal melanoma
title_short Hemorrhagic choroidal melanoma
title_full Hemorrhagic choroidal melanoma
title_fullStr Hemorrhagic choroidal melanoma
title_full_unstemmed Hemorrhagic choroidal melanoma
title_sort hemorrhagic choroidal melanoma
publisher Elsevier
series American Journal of Ophthalmology Case Reports
issn 2451-9936
publishDate 2018-06-01
description Purpose: To demonstrate the clinical pathologic correlation in a hemorrhagic choroidal melanoma. Observations: A 52 year old patient presented with a large choroidal mass associated with vitreous and retinal hemorrhage. The eye was enucleated and histopathology demonstrated epithelioid-type MART1 positive tumor cells consistent with choroidal melanoma. The tumor had broken through Bruch's membrane, which led to localized vascular compression with bleeding into the subretinal space, retina and vitreous. Conclusions and importance: Choroidal melanoma rarely presents with hemorrhage. Tumor rupture through Bruch's membrane may result in a tourniquet effect on the tumor vasculature leading to massive hemorrhage, as in this case. A high level of clinical suspicion is required to make the diagnosis. Keywords: Choroidal melanoma, Hemorrhagic melanoma
url http://www.sciencedirect.com/science/article/pii/S2451993617303389
work_keys_str_mv AT patrickoellers hemorrhagicchoroidalmelanoma
AT nataliewolkow hemorrhagicchoroidalmelanoma
AT frederickajakobiec hemorrhagicchoroidalmelanoma
AT ivanakkim hemorrhagicchoroidalmelanoma
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