Tyrosine Kinase Inhibitor Tyrphostin AG490 Inhibits Osteoclast Differentiation in Collagenase-Induced Osteoarthritis
The janus kinase (JAK)-signal transducer and activator of transcription (STAT) cascade plays a principal role in the signaling of a vast array of cytokines and growth factors which stimulates diverse cellular functions and immune responses. Osteoarthritis (OA) is the most common joint disease in the...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2014-05-01
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Series: | European Journal of Inflammation |
Online Access: | https://doi.org/10.1177/1721727X1401200212 |