Tyrosine Kinase Inhibitor Tyrphostin AG490 Inhibits Osteoclast Differentiation in Collagenase-Induced Osteoarthritis

The janus kinase (JAK)-signal transducer and activator of transcription (STAT) cascade plays a principal role in the signaling of a vast array of cytokines and growth factors which stimulates diverse cellular functions and immune responses. Osteoarthritis (OA) is the most common joint disease in the...

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Bibliographic Details
Main Authors: V. Gyurkovska, P. Dimitrova, N. Ivanovska
Format: Article
Language:English
Published: SAGE Publishing 2014-05-01
Series:European Journal of Inflammation
Online Access:https://doi.org/10.1177/1721727X1401200212