Epigenetics of gene expression in human hepatoma cells: expression profiling the response to inhibition of DNA methylation and histone deacetylation

Epigenetics of gene expression in human hepatoma cells: expression profiling the response to inhibition of DNA methylation and histone deacetylation

<p>Abstract</p> <p>Background</p> <p>DNA methylation and histone deacetylation are epigenetic mechanisms that play major roles in eukaryotic gene regulation. We hypothesize that many genes in the human hepatoma cell line HepG2 are regulated by DNA methylation and histon...

Full description

Bibliographic Details
Main Authors:	Edenberg Howard J, Dannenberg Luke O
Format:	Article
Language:	English
Published:	BMC 2006-07-01
Series:	BMC Genomics
Online Access:	http://www.biomedcentral.com/1471-2164/7/181

Similar Items

Inhibition of Histone Deacetylation and DNA Methylation Improves Gene Expression Mediated by the Adeno-Associated Virus/Phage in Cancer Cells
by: Amin Hajitou, et al.
Published: (2013-10-01)

Cancer-type regulation of MIG-6 expression by inhibitors of methylation and histone deacetylation.
by: Yu-Wen Zhang, et al.
Published: (2012-01-01)

Gene expression analysis reveals that histone deacetylation sites may serve as partitions of chromatin gene expression domains
by: Zhao Hongyu, et al.
Published: (2005-03-01)

Global profiling of histone and DNA methylation reveals epigenetic-based regulation of gene expression during epithelial to mesenchymal transition in prostate cells
by: Li Wen-Cheng, et al.
Published: (2010-11-01)

TET2 Inhibits <i>PD-L1</i> Gene Expression in Breast Cancer Cells through Histone Deacetylation
by: Yinghui Shen, et al.
Published: (2021-05-01)

The prima donna of epigenetics: the regulation of gene expression by DNA methylation
by: K.F. Santos, et al.
Published: (2005-10-01)

Gene silencing mediated by genome targeted histone deacetylation
by: Pike, Joanna Elizabeth
Published: (2002)

Epigenetic therapy: use of agents targeting deacetylation and methylation in cancer management
by: Ho AS, et al.
Published: (2013-03-01)

Epigenetic Alterations Induced by Photothrombotic Stroke in the Rat Cerebral Cortex: Deacetylation of Histone h3, Upregulation of Histone Deacetylases and Histone Acetyltransferases
by: Svetlana Demyanenko, et al.
Published: (2019-06-01)

The Interplay between Toxic and Essential Metals for Their Uptake and Translocation Is Likely Governed by DNA Methylation and Histone Deacetylation in Maize
by: Sarfraz Shafiq, et al.
Published: (2020-09-01)

Transcriptional suppression, DNA methylation, and histone deacetylation of the regulator of G-protein signaling 10 (RGS10) gene in ovarian cancer cells.
by: Mourad W Ali, et al.
Published: (2013-01-01)

Role of methionine on epigenetic modification of DNA methylation and gene expression in animals
by: Naifeng Zhang
Published: (2018-03-01)

Histone acetylation and deacetylation in ischemic stroke
by: Anatoly B Uzdensky, et al.
Published: (2021-01-01)

Integrated epigenome profiling of repressive histone modifications, DNA methylation and gene expression in normal and malignant urothelial cells.
by: Ewa Dudziec, et al.
Published: (2012-01-01)

DNA Methylation and Gene Expression Profiling of Ewing Sarcoma Primary Tumors Reveal Genes That Are Potential Targets of Epigenetic Inactivation
by: Nikul Patel, et al.
Published: (2012-01-01)

Methylation-sensitive expression of a DNA demethylase gene serves as an epigenetic rheostat.
by: Ben P Williams, et al.
Published: (2015-03-01)

Methylation-Sensitive Expression of a DNA Demethylase Gene Serves As an Epigenetic Rheostat
by: Williams, Ben P., et al.
Published: (2015)

Selective Inhibition of Histone Deacetylation in Melanoma Increases Targeted Gene Delivery by a Bacteriophage Viral Vector
by: Samuel Campbell, et al.
Published: (2018-04-01)

Epigenetic determinants in rheumatoid arthritis: the influence of DNA methylation and histone modifications
by: Bogdan Kolarz, et al.
Published: (2017-12-01)

Characterization of the histone deacetylation activity of the yeast silencing gene SIR2
by: Armstrong, Christopher Mark, 1972-
Published: (2005)

Histone Deacetylation Inhibitors as Modulators of Regulatory T Cells
by: Andreas von Knethen, et al.
Published: (2020-03-01)

Histone Deacetylation Inhibitors as Therapy Concept in Sepsis
by: Andreas von Knethen, et al.
Published: (2019-01-01)

Tbx1 represses Mef2c gene expression and is correlated with histone 3 deacetylation of the anterior heart field enhancer
by: Luna Simona Pane, et al.
Published: (2018-09-01)

Genome-wide chromatin accessibility, DNA methylation and gene expression analysis of histone deacetylase inhibition in triple-negative breast cancer
by: Matias A. Bustos, et al.
Published: (2017-06-01)

Epigenetic Heterogeneity of B-Cell Lymphoma: DNA Methylation, Gene Expression and Chromatin States
by: Lydia Hopp, et al.
Published: (2015-09-01)

The expression profiling of histone gene in male spermatogenesis
by: Tung-chia cheng, et al.
Published: (2006)

DNA methylation and gene expression changes in monozygotic twins discordant for psoriasis: identification of epigenetically dysregulated genes.
by: Kristina Gervin, et al.
Published: (2012-01-01)

DNA Methylation and Gene Expression Profiling for Parkinson’s Biomarker Discovery
Published: (2019)

Comprehensive analysis of DNA methylation and gene expression profiles in cholangiocarcinoma
by: Cheng Zhang, et al.
Published: (2019-12-01)

Whole Genome DNA Methylation and Gene Expression Profiling of Oropharyngeal Cancer Patients in North-Eastern India: Identification of Epigenetically Altered Gene Expression Reveals Potential Biomarkers
by: Lastborn Marthong, et al.
Published: (2020-10-01)

Integration of sperm ncRNA-directed DNA methylation and DNA methylation-directed histone retention in epigenetic transgenerational inheritance
by: Daniel Beck, et al.
Published: (2021-01-01)

Heritable epigenetic responses to environmental challenges : Effects on behaviour, gene expression and DNA-methylation in the chicken
by: Nätt, Daniel
Published: (2011)

Inhibition of Ehmt2 promotes histone deacetylation-mediated neuronal differentiation of neural stem cells
by: Chen, Yen-Po, et al.
Published: (2011)

The gene expression profiles in hepatoma A2 cells during the manipulation of androgen
by: Wei-Chih Lin, et al.
Published: (2002)

The Role of Sulforaphane in Epigenetic Mechanisms, Including Interdependence between Histone Modification and DNA Methylation
by: Agnieszka Kaufman-Szymczyk, et al.
Published: (2015-12-01)

Protein Profiling and Histone Deacetylation Activities in Somaclonal Variants of Oil Palm (Elaeis guineensis Jacq.)
by: Jamilah Syafawati Yaacob, et al.
Published: (2013-01-01)

Photoperiodic regulation of flowering time through periodic histone deacetylation of the florigen gene FT.
by: Xiaofeng Gu, et al.
Published: (2013-09-01)

Search for down-regulated genes by epigenetic changes in human hepatoma via DNA demethylation approaches
by: Chiu-Ping Wu, et al.
Published: (2005)

Integrative DNA methylation and gene expression analyses identify DNA packaging and epigenetic regulatory genes associated with low motility sperm.
by: Sara E Pacheco, et al.
Published: (2011-01-01)

Suppressor of cytokine signaling (SOCS) genes are silenced by DNA hypermethylation and histone deacetylation and regulate response to radiotherapy in cervical cancer cells.
by: Moon-Hong Kim, et al.
Published: (2015-01-01)