Embryonic vascular endothelial cells are malleable to reprogramming via Prox1 to a lymphatic gene signature

<p>Abstract</p> <p>Background</p> <p><it>In vivo </it>studies demonstrate that the Prox1 transcription factor plays a critical role in the development of the early lymphatic system. Upon Prox1 expression, early lymphatic endothelial cells differentiate from...

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Bibliographic Details
Main Authors: Cruz Maribelle, Petrova Tatiana V, Nguyen Vicky PKH, Kim Harold, Alitalo Kari, Dumont Daniel J
Format: Article
Language:English
Published: BMC 2010-06-01
Series:BMC Developmental Biology
Online Access:http://www.biomedcentral.com/1471-213X/10/72