The dynamic organization of fungal acetyl-CoA carboxylase

Acetyl-CoA carboxylases are central regulatory hubs of fatty acid metabolism and are important targets for drug development in obesity and cancer. Here, the authors demonstrate that the regulation of these highly dynamic enzymes in fungi is governed by a mechanism based on phosphorylation-dependent...

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Bibliographic Details
Main Authors: Moritz Hunkeler, Edward Stuttfeld, Anna Hagmann, Stefan Imseng, Timm Maier
Format: Article
Language:English
Published: Nature Publishing Group 2016-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11196