A Missense Mutation in OPA1 Causes Dominant Optic Atrophy in a Chinese Family

A Missense Mutation in OPA1 Causes Dominant Optic Atrophy in a Chinese Family

Background. To investigate the genetic causes and clinical characteristics of dominant optic atrophy (DOA) in a Chinese family. Methods. A 5-generation pedigree of 35 family members including 12 individuals affected with DOA was recruited from Shenzhen Eye Hospital, China. Four affected family membe...

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Bibliographic Details
Main Authors:	Shaoyi Mei, Xiaosheng Huang, Lin Cheng, Shiming Peng, Tianhui Zhu, Liang Chen, Yan Wang, Jun Zhao
Format:	Article
Language:	English
Published:	Hindawi Limited 2019-01-01
Series:	Journal of Ophthalmology
Online Access:	http://dx.doi.org/10.1155/2019/1424928

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