Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness
Male-pattern baldness is a common condition in which hair is progressively lost from the scalp. Here, the authors find 23 new genetic variants associated with this condition and suggest that it is not an isolated trait but may share an underlying biological basis with various diseases.
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| Format: | Article |
| Language: | English |
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Nature Publishing Group
2017-03-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms14694 |
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doaj-d9af447ee8394cd192c3c73035f7e0732021-05-11T07:51:41ZengNature Publishing GroupNature Communications2041-17232017-03-01811810.1038/ncomms14694Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldnessStefanie Heilmann-Heimbach0Christine Herold1Lara M. Hochfeld2Axel M. Hillmer3Dale R. Nyholt4Julian Hecker5Asif Javed6Elaine G. Y. Chew7Sonali Pechlivanis8Dmitriy Drichel9Xiu Ting Heng10Ricardo C. -H. del Rosario11Heide L. Fier12Ralf Paus13Rico Rueedi14Tessel E. Galesloot15Susanne Moebus16Thomas Anhalt17Shyam Prabhakar18Rui Li19Stavroula Kanoni20George Papanikolaou21Zoltán Kutalik22Panos Deloukas23Michael P. Philpott24Gérard Waeber25Tim D. Spector26Peter Vollenweider27Lambertus A. L. M. Kiemeney28George Dedoussis29J. Brent Richards30Michael Nothnagel31Nicholas G. Martin32Tim Becker33David A. Hinds34Markus M. Nöthen35Institute of Human Genetics, University of BonnGerman Center for Neurodegenerative DisordersInstitute of Human Genetics, University of BonnCancer Therapeutics and Stratified Oncology, Genome Institute of SingaporeInstitute of Health and Biomedical Innovation, Queensland University of TechnologyInstitute of Genomic Mathematics, University of BonnCancer Therapeutics and Stratified Oncology, Genome Institute of SingaporeCancer Therapeutics and Stratified Oncology, Genome Institute of SingaporeInstitute of Medical Informatics, Biometry and Epidemiology, Medical Faculty, University of Duisburg-EssenCologne Center for Genomics, University of CologneCancer Therapeutics and Stratified Oncology, Genome Institute of SingaporeComputational and Systems Biology, Genome Institute of SingaporeInstitute of Genomic Mathematics, University of BonnDermatology Research Centre, Institute of Inflammation and Repair, University of ManchesterDepartment of Computational Biology, University of LausanneDepartment for Health Evidence, Radboud Institute for Health Sciences, Radboud University Medical CenterInstitute of Medical Informatics, Biometry and Epidemiology, Medical Faculty, University of Duisburg-EssenInstitute of Human Genetics, University of BonnComputational and Systems Biology, Genome Institute of SingaporeDepartments of Medicine, Centre for Clinical Epidemiology, Genetics and Epidemiology, Lady Davis Institute for Medical Research, Jewish General Hospital, McGill UniversityWilliam Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of LondonDepartment of Nutrition and Dietetics, School of Health Sciences and Education, Harokopio UniversitySwiss Institute of BioinformaticsWilliam Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of LondonCentre for Cell Biology and Cutaneous Research Barts and The London School of Medicine and Dentistry, Queen Mary University of LondonDepartment of Internal Medicine, Lausanne University Hospital (CHUV)Department of Twin Research & Genetic Epidemiology, King's College LondonDepartment of Internal Medicine, Lausanne University Hospital (CHUV)Department for Health Evidence, Radboud Institute for Health Sciences, Radboud University Medical CenterDepartment of Nutrition and Dietetics, School of Health Sciences and Education, Harokopio UniversityDepartments of Medicine, Centre for Clinical Epidemiology, Genetics and Epidemiology, Lady Davis Institute for Medical Research, Jewish General Hospital, McGill UniversityCologne Center for Genomics, University of CologneQIMR Berghofer Medical Research InstituteInstitute for Community Medicine, Ernst Moritz Arndt University Greifswald23andMe Inc.Institute of Human Genetics, University of BonnMale-pattern baldness is a common condition in which hair is progressively lost from the scalp. Here, the authors find 23 new genetic variants associated with this condition and suggest that it is not an isolated trait but may share an underlying biological basis with various diseases.https://doi.org/10.1038/ncomms14694 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Stefanie Heilmann-Heimbach Christine Herold Lara M. Hochfeld Axel M. Hillmer Dale R. Nyholt Julian Hecker Asif Javed Elaine G. Y. Chew Sonali Pechlivanis Dmitriy Drichel Xiu Ting Heng Ricardo C. -H. del Rosario Heide L. Fier Ralf Paus Rico Rueedi Tessel E. Galesloot Susanne Moebus Thomas Anhalt Shyam Prabhakar Rui Li Stavroula Kanoni George Papanikolaou Zoltán Kutalik Panos Deloukas Michael P. Philpott Gérard Waeber Tim D. Spector Peter Vollenweider Lambertus A. L. M. Kiemeney George Dedoussis J. Brent Richards Michael Nothnagel Nicholas G. Martin Tim Becker David A. Hinds Markus M. Nöthen |
| spellingShingle |
Stefanie Heilmann-Heimbach Christine Herold Lara M. Hochfeld Axel M. Hillmer Dale R. Nyholt Julian Hecker Asif Javed Elaine G. Y. Chew Sonali Pechlivanis Dmitriy Drichel Xiu Ting Heng Ricardo C. -H. del Rosario Heide L. Fier Ralf Paus Rico Rueedi Tessel E. Galesloot Susanne Moebus Thomas Anhalt Shyam Prabhakar Rui Li Stavroula Kanoni George Papanikolaou Zoltán Kutalik Panos Deloukas Michael P. Philpott Gérard Waeber Tim D. Spector Peter Vollenweider Lambertus A. L. M. Kiemeney George Dedoussis J. Brent Richards Michael Nothnagel Nicholas G. Martin Tim Becker David A. Hinds Markus M. Nöthen Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness Nature Communications |
| author_facet |
Stefanie Heilmann-Heimbach Christine Herold Lara M. Hochfeld Axel M. Hillmer Dale R. Nyholt Julian Hecker Asif Javed Elaine G. Y. Chew Sonali Pechlivanis Dmitriy Drichel Xiu Ting Heng Ricardo C. -H. del Rosario Heide L. Fier Ralf Paus Rico Rueedi Tessel E. Galesloot Susanne Moebus Thomas Anhalt Shyam Prabhakar Rui Li Stavroula Kanoni George Papanikolaou Zoltán Kutalik Panos Deloukas Michael P. Philpott Gérard Waeber Tim D. Spector Peter Vollenweider Lambertus A. L. M. Kiemeney George Dedoussis J. Brent Richards Michael Nothnagel Nicholas G. Martin Tim Becker David A. Hinds Markus M. Nöthen |
| author_sort |
Stefanie Heilmann-Heimbach |
| title |
Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness |
| title_short |
Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness |
| title_full |
Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness |
| title_fullStr |
Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness |
| title_full_unstemmed |
Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness |
| title_sort |
meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2017-03-01 |
| description |
Male-pattern baldness is a common condition in which hair is progressively lost from the scalp. Here, the authors find 23 new genetic variants associated with this condition and suggest that it is not an isolated trait but may share an underlying biological basis with various diseases. |
| url |
https://doi.org/10.1038/ncomms14694 |
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