Evidence for a Novel Mechanism of Influenza Virus-Induced Type I Interferon Expression by a Defective RNA-Encoded Protein.

Evidence for a Novel Mechanism of Influenza Virus-Induced Type I Interferon Expression by a Defective RNA-Encoded Protein.

Influenza A virus (IAV) defective RNAs are generated as byproducts of error-prone viral RNA replication. They are commonly derived from the larger segments of the viral genome and harbor deletions of various sizes resulting in the generation of replication incompatible viral particles. Furthermore,...

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Bibliographic Details
Main Authors: Yvonne Boergeling, Timofey S Rozhdestvensky, Mirco Schmolke, Patricia Resa-Infante, Thomas Robeck, Gerrit Randau, Thorsten Wolff, Gülsah Gabriel, Jürgen Brosius, Stephan Ludwig
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-05-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1004924

Internet

https://doi.org/10.1371/journal.ppat.1004924

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