The Y172 Monoclonal Antibody Against p-c-Jun (Ser63) Is a Marker of the Postsynaptic Compartment of C-Type Cholinergic Afferent Synapses on Motoneurons

The Y172 Monoclonal Antibody Against p-c-Jun (Ser63) Is a Marker of the Postsynaptic Compartment of C-Type Cholinergic Afferent Synapses on Motoneurons

C-bouton-type cholinergic afferents exert an important function in controlling motoneuron (MN) excitability. During the immunocytochemical analysis of the role of c-Jun in MNs with a monoclonal (clone Y172) antibody against phospho (p)-c-Jun (serine [Ser]63), unexpected labeling was identified in th...

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Bibliographic Details
Main Authors: Alaó Gatius, Olga Tarabal, Paula Cayuela, Anna Casanovas, Lídia Piedrafita, Sara Salvany, Sara Hernández, Rosa M. Soler, Josep E. Esquerda, Jordi Calderó
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Cellular Neuroscience
Subjects:
motoneuron
C-bouton
phospho-c-Jun
Y172 antibody
endoplasmic reticulum-plasma membrane contacts
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00582/full

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