Asymmetric division events promote variability in cell cycle duration in animal cells and Escherichia coli

Asymmetric division events promote variability in cell cycle duration in animal cells and Escherichia coli

We know that variations in cell cycle duration between cells naturally occur but the mechanisms are largely unknown. Here, using lineage tracking, hierarchical clustering and Monte Carlo methods, the authors show that large differences in granddaughter cell cycle duration are driven by asymmetric di...

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Bibliographic Details
Main Authors: Ulrich Berge, Daria Bochenek, Ralf Schnabel, Arne Wehling, Timm Schroeder, Tanja Stadler, Ruth Kroschewski
Format: Article
Language:English
Published: Nature Publishing Group 2019-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09413-5
Description
Summary:We know that variations in cell cycle duration between cells naturally occur but the mechanisms are largely unknown. Here, using lineage tracking, hierarchical clustering and Monte Carlo methods, the authors show that large differences in granddaughter cell cycle duration are driven by asymmetric divisions.
ISSN:2041-1723

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