Analysis of factors that influence the outcomes of labor induction with intravenous synthetic oxytocin infusion in term pregnancy with favourable bishop score

• Main Authors: Mahmut Kuntay Kokanali, Demet Kokanali, Ali irfan Guzel, Hasan Onur Topcu, Sabri Cavkaytar, Melike Doganay
• Format: Article
• Language: English
• Published: Cukurova University 2015-06-01
• Series: Çukurova Üniversitesi Tıp Fakültesi Dergisi
• Subjects: term pregnancy; bishop score; oxytocin; labor induction
• Online Access: http://www.scopemed.org/fulltextpdf.php?mno=173483

Purpose: To investigate the factors that influence the success of labor induction with synthetic intravenous oxytocin infusion in term pregnancies with favourable Bishop score. Material and Methods: 150 pregnant women with completed 37 weeks of gestation and Bishop score>6 who had single and cephalic presentation of pregnancy and were decided to underwent labor induction with intravenous oxytocin infusion were included in the study. Labor induction was considered unsuccessful if a vaginal delivery did not occur within 24 hours after the onset of loxytocin infusion or a cesarean section was performed during oxytocin infusion due to foetal distress, cephalopelvic disproportion or failure to progress in labor. Multivariable regression were used to identify odds of induction success. Results: Out of 150 women, induction of labor was unsuccessful in 23 (15.3%). Multivariate analysis demonstrated that nulliparity, shorter gestation period, persistent occiput posterior presentation and greater birth weight were independent risk factors for the induction failure. ROC curve analysis stated that gestation period of <270 days predict induction failure with a sensitivity of 60.9% and a spesificity of 92.9% while value of >3445-gram-birth weight has a sensitivity of 82.6% and a spesificity of 71.7% for the prediction of failure. Conclusion: Nulliparity, shorter gestation period, persistent occiput posterior presentation and greater birth weight increase the failure risk of labor induction with intravenous synthetic oxytocin infusion. [Cukurova Med J 2015; 40(2.000): 317-325]