Variation in the gene coding for the M5 Muscarinic receptor (<it>CHRM5</it>) influences cigarette dose but is not associated with dependence to drugs of addiction: evidence from a prospective population based cohort study of young adults

Variation in the gene coding for the M5 Muscarinic receptor (<it>CHRM5</it>) influences cigarette dose but is not associated with dependence to drugs of addiction: evidence from a prospective population based cohort study of young adults

<p>Abstract</p> <p>Background</p> <p>The mesolimbic structures of the brain are important in the anticipation and perception of reward. Moreover, many drugs of addiction elicit their response in these structures. The M5 muscarinic receptor (M5R) is expressed in dopamine...

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Bibliographic Details
Main Authors: Olsson Craig A, Lotfi-Miri Mehrnoush, Anney Richard JL, Reid Sophie C, Hemphill Sheryl A, Patton George C
Format: Article
Language:English
Published: BMC 2007-07-01
Series:BMC Genetics
Online Access:http://www.biomedcentral.com/1471-2156/8/46

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