SWEF Proteins Distinctly Control Maintenance and Differentiation of Hematopoietic Stem Cells.

SWEF Proteins Distinctly Control Maintenance and Differentiation of Hematopoietic Stem Cells.

SWAP-70 and DEF6, two proteins that feature similar domain and motif arrangements, are mainly known for their functions in differentiated hematopoietic cells. Both proteins interact with and regulate RhoGTPases and F-actin dynamics, yet their role in hematopoietic stem and precursor cells (HSPCs) re...

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Bibliographic Details
Main Authors: Tatsiana Ripich, Carlos Andrés Chacón-Martínez, Luise Fischer, Alessandra Pernis, Nadine Kiessling, Annette I Garbe, Rolf Jessberger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4999197?pdf=render

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