Novel Phenolic Compounds as Potential Dual EGFR and COX-2 Inhibitors: Design, Semisynthesis, in vitro Biological Evaluation and in silico Insights

Novel Phenolic Compounds as Potential Dual EGFR and COX-2 Inhibitors: Design, Semisynthesis, in vitro Biological Evaluation and in silico Insights

Mohamed A Abdelgawad,1 Arafa Musa,2 Atiah H Almalki,3,4 Sami I Alzarea,5 Ehab M Mostafa,2 Mostafa M Hegazy,6 Gomaa Mostafa-Hedeab,7 Mohammed M Ghoneim,6,8 Della GT Parambi,1 Rania B Bakr,1 Nayef S Al-Muaikel,9 Abdullah S Alanazi,10,11 Metab Alharbi,12 Waqas Ahmad,13 Syed NA Bukhari,1 Mohammad M Al-S...

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Bibliographic Details
Main Authors: Abdelgawad MA, Musa A, Almalki AH, Alzarea SI, Mostafa EM, Hegazy MM, Mostafa-Hedeab G, Ghoneim MM, Parambi DGT, Bakr RB, Al-Muaikel NS, Alanazi AS, Alharbi M, Ahmad W, Bukhari SNA, Al-Sanea MM
Format: Article
Language:English
Published: Dove Medical Press 2021-05-01
Series:Drug Design, Development and Therapy
Subjects:
kinase inhibitors
anti-inflammatory
multitarget agents
braf
anticancer
Online Access:https://www.dovepress.com/novel-phenolic-compounds-as-potential-dual-egfr-and-cox-2-inhibitors-d-peer-reviewed-fulltext-article-DDDT

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https://www.dovepress.com/novel-phenolic-compounds-as-potential-dual-egfr-and-cox-2-inhibitors-d-peer-reviewed-fulltext-article-DDDT

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