LACTOFERIN IN THE PROBLEM OF ANTI-INFECTIOUS PROTECTION OF BABIES IN THEIR FIRST YEAR OF LIVING

The author  summarizes  the  results  of research  of the  antibacterial,  antiviral  and  antifungal  properties  of multifunctional  human protein  — lactoferrin,  in order  to determine  the prospects  for its use in the prevention  and  treatment  of infectious  diseases  of children in their fi...

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Main Authors: P. E. Sadchikov, I. G. Goldman, L. S. Namazova-Baranova, G. V. Yatsik, T. E. Borovik, A. D. Chernousov, А. I. Romanchenko, E. R. Sadchikova, O. L. Lukoyanova, N. G. Zvonkova, I. A. Belyaeva
Format: Article
Language:English
Published: Paediatrician Publishers, LLC 2017-02-01
Series:Pediatričeskaâ Farmakologiâ
Subjects:
Online Access:https://www.pedpharma.ru/jour/article/view/1488
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spelling doaj-d9789a99fe804cbb872311edfb81dd4f2021-07-28T16:32:40ZengPaediatrician Publishers, LLCPediatričeskaâ Farmakologiâ1727-57762500-30892017-02-0113660761310.15690/pf.v13i6.16771465LACTOFERIN IN THE PROBLEM OF ANTI-INFECTIOUS PROTECTION OF BABIES IN THEIR FIRST YEAR OF LIVINGP. E. Sadchikov0I. G. Goldman1L. S. Namazova-Baranova2G. V. Yatsik3T. E. Borovik4A. D. Chernousov5А. I. Romanchenko6E. R. Sadchikova7O. L. Lukoyanova8N. G. Zvonkova9I. A. Belyaeva10Scientific Center of Children’s HealthInstitute of Gene BiologyScientific Center of Children’s Health; Sechenov First Moscow State Medical University; N.I. Pirogov Russian National Research Medical UniversityScientific Center of Children’s HealthScientific Center of Children’s Health; Sechenov First Moscow State Medical UniversityInstitute of Gene Biology; Institute of Immunology, State Science CenterInstitute of Gene BiologyInstitute of Gene BiologyScientific Center of Children’s HealthScientific Center of Children’s Health; Sechenov First Moscow State Medical UniversityScientific Center of Children’s HealthThe author  summarizes  the  results  of research  of the  antibacterial,  antiviral  and  antifungal  properties  of multifunctional  human protein  — lactoferrin,  in order  to determine  the prospects  for its use in the prevention  and  treatment  of infectious  diseases  of children in their first year of life. The mechanisms of anti-infectious effect of this protein with breastfed children have been described. Basic differences between human lactoferrin and cattle lactoferrin have been shown. Biotechnology of obtaining recombinant human lactoferrin from the milk of genetically engineered dairy animals (goat-producers) has been described. According to the studies, both by physical and chemical parameters and biological activity, human lactoferrin, obtained from milk-producing  goats, corresponds to its natural counterpart.https://www.pedpharma.ru/jour/article/view/1488childrenlactoferrinantibiotics-resistant microflorainfection pathology
collection DOAJ
language English
format Article
sources DOAJ
author P. E. Sadchikov
I. G. Goldman
L. S. Namazova-Baranova
G. V. Yatsik
T. E. Borovik
A. D. Chernousov
А. I. Romanchenko
E. R. Sadchikova
O. L. Lukoyanova
N. G. Zvonkova
I. A. Belyaeva
spellingShingle P. E. Sadchikov
I. G. Goldman
L. S. Namazova-Baranova
G. V. Yatsik
T. E. Borovik
A. D. Chernousov
А. I. Romanchenko
E. R. Sadchikova
O. L. Lukoyanova
N. G. Zvonkova
I. A. Belyaeva
LACTOFERIN IN THE PROBLEM OF ANTI-INFECTIOUS PROTECTION OF BABIES IN THEIR FIRST YEAR OF LIVING
Pediatričeskaâ Farmakologiâ
children
lactoferrin
antibiotics-resistant microflora
infection pathology
author_facet P. E. Sadchikov
I. G. Goldman
L. S. Namazova-Baranova
G. V. Yatsik
T. E. Borovik
A. D. Chernousov
А. I. Romanchenko
E. R. Sadchikova
O. L. Lukoyanova
N. G. Zvonkova
I. A. Belyaeva
author_sort P. E. Sadchikov
title LACTOFERIN IN THE PROBLEM OF ANTI-INFECTIOUS PROTECTION OF BABIES IN THEIR FIRST YEAR OF LIVING
title_short LACTOFERIN IN THE PROBLEM OF ANTI-INFECTIOUS PROTECTION OF BABIES IN THEIR FIRST YEAR OF LIVING
title_full LACTOFERIN IN THE PROBLEM OF ANTI-INFECTIOUS PROTECTION OF BABIES IN THEIR FIRST YEAR OF LIVING
title_fullStr LACTOFERIN IN THE PROBLEM OF ANTI-INFECTIOUS PROTECTION OF BABIES IN THEIR FIRST YEAR OF LIVING
title_full_unstemmed LACTOFERIN IN THE PROBLEM OF ANTI-INFECTIOUS PROTECTION OF BABIES IN THEIR FIRST YEAR OF LIVING
title_sort lactoferin in the problem of anti-infectious protection of babies in their first year of living
publisher Paediatrician Publishers, LLC
series Pediatričeskaâ Farmakologiâ
issn 1727-5776
2500-3089
publishDate 2017-02-01
description The author  summarizes  the  results  of research  of the  antibacterial,  antiviral  and  antifungal  properties  of multifunctional  human protein  — lactoferrin,  in order  to determine  the prospects  for its use in the prevention  and  treatment  of infectious  diseases  of children in their first year of life. The mechanisms of anti-infectious effect of this protein with breastfed children have been described. Basic differences between human lactoferrin and cattle lactoferrin have been shown. Biotechnology of obtaining recombinant human lactoferrin from the milk of genetically engineered dairy animals (goat-producers) has been described. According to the studies, both by physical and chemical parameters and biological activity, human lactoferrin, obtained from milk-producing  goats, corresponds to its natural counterpart.
topic children
lactoferrin
antibiotics-resistant microflora
infection pathology
url https://www.pedpharma.ru/jour/article/view/1488
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