Human bone marrow mesenchymal stem cells-derived exosomes alleviate liver fibrosis through the Wnt/β-catenin pathway

Human bone marrow mesenchymal stem cells-derived exosomes alleviate liver fibrosis through the Wnt/β-catenin pathway

Abstract Background Mesenchymal stem cells (MSCs) are increasingly being applied as a therapy for liver fibrosis. Exosomes possess similar functions to their parent cells; however, they are safe and effective cell-free reagents with controllable and predictable outcomes. In this study, we investigat...

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Bibliographic Details
Main Authors: Xiaoli Rong, Junzhi Liu, Xia Yao, Tiechao Jiang, Yimin Wang, Feng Xie
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Stem Cell Research & Therapy
Subjects:
hBM-MSCs
Exosomes
Liver fibrosis
Wnt/β-catenin
Online Access:http://link.springer.com/article/10.1186/s13287-019-1204-2

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