PremPRI: Predicting the Effects of Missense Mutations on Protein–RNA Interactions

PremPRI: Predicting the Effects of Missense Mutations on Protein–RNA Interactions

Protein–RNA interactions are crucial for many cellular processes, such as protein synthesis and regulation of gene expression. Missense mutations that alter protein–RNA interaction may contribute to the pathogenesis of many diseases. Here, we introduce a new computational method PremPRI, which predi...

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Bibliographic Details
Main Authors: Ning Zhang, Haoyu Lu, Yuting Chen, Zefeng Zhu, Qing Yang, Shuqin Wang, Minghui Li
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
Mutation
Protein–RNA interaction
binding affinity change
computational approach
Online Access:https://www.mdpi.com/1422-0067/21/15/5560

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https://www.mdpi.com/1422-0067/21/15/5560

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