Temozolomide and cisplatin in relapsed/refractory acute leukemia

Temozolomide and cisplatin in relapsed/refractory acute leukemia

<p>Abstract</p> <p>Cisplatin depletes MGMT and increases the sensitivity of leukemia cells to temozolomide. We performed a phase I study of cisplatin and temozolomide in patients with relapsed and refractory acute leukemia. Fifteen patients had AML, 3 had ALL, and 2 had biphenotypi...

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Bibliographic Details
Main Authors: Rasul Muhammad, Ponce Doris, Katragadda Sreedhar, Seiter Karen, Ahmed Nasir
Format: Article
Language:English
Published: BMC 2009-05-01
Series:Journal of Hematology & Oncology
Online Access:http://www.jhoonline.org/content/2/1/21

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