The Long Noncoding RNA HOTAIR in Breast Cancer: Does Autophagy Play a Role?

The Long Noncoding RNA HOTAIR in Breast Cancer: Does Autophagy Play a Role?

HOTAIR (HOX transcript antisense RNA) plays a critical role in chromatin dynamics through the interaction with histone modifiers resulting in transcriptional gene silencing. The promoter of the HOTAIR gene contains multiple estrogen response elements (EREs) and is transcriptionally activated by estr...

Full description

Bibliographic Details
Main Authors: Elżbieta Pawłowska, Joanna Szczepanska, Janusz Blasiak
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:International Journal of Molecular Sciences
Subjects:
HOTAIR
breast cancer
autophagy
chromatin remodeling
cancer progression
miR-34a
matrix metalloproteinases
lncRNA–miRNA axis
Online Access:https://www.mdpi.com/1422-0067/18/11/2317

Similar Items

Similar Items