The role of the gut microbiome during host ageing [version 1; referees: 2 approved]

The role of the gut microbiome during host ageing [version 1; referees: 2 approved]

Gut microbial communities participate in key aspects of host biology, including development, nutrient absorption, immunity and disease. During host ageing, intestinal microbes undergo dramatic changes in composition and function and can shift from commensal to pathogenic. However, whether they play...

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Bibliographic Details
Main Authors: Jens Seidel, Dario Riccardo Valenzano
Format: Article
Language:English
Published: F1000 Research Ltd 2018-07-01
Series:F1000Research
Online Access:https://f1000research.com/articles/7-1086/v1
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spelling doaj-d9581b731bff47a1bd89f196cdc07f592020-11-25T02:49:00ZengF1000 Research LtdF1000Research2046-14022018-07-01710.12688/f1000research.15121.116474The role of the gut microbiome during host ageing [version 1; referees: 2 approved]Jens Seidel0Dario Riccardo Valenzano1Max Planck Institute for Biology of Ageing, Cologne, GermanyMax Planck Institute for Biology of Ageing, Cologne, GermanyGut microbial communities participate in key aspects of host biology, including development, nutrient absorption, immunity and disease. During host ageing, intestinal microbes undergo dramatic changes in composition and function and can shift from commensal to pathogenic. However, whether they play a causal role in host ageing and life span has remained an open question for a long time. Recent work in model organisms has revealed for the first time that gut microbes can modulate ageing, opening new questions and opportunities to uncover novel ageing-modulating mechanisms and to design anti-ageing interventions by targeting the gut microbiota.https://f1000research.com/articles/7-1086/v1
collection DOAJ
language English
format Article
sources DOAJ
author Jens Seidel
Dario Riccardo Valenzano
spellingShingle Jens Seidel
Dario Riccardo Valenzano
The role of the gut microbiome during host ageing [version 1; referees: 2 approved]
F1000Research
author_facet Jens Seidel
Dario Riccardo Valenzano
author_sort Jens Seidel
title The role of the gut microbiome during host ageing [version 1; referees: 2 approved]
title_short The role of the gut microbiome during host ageing [version 1; referees: 2 approved]
title_full The role of the gut microbiome during host ageing [version 1; referees: 2 approved]
title_fullStr The role of the gut microbiome during host ageing [version 1; referees: 2 approved]
title_full_unstemmed The role of the gut microbiome during host ageing [version 1; referees: 2 approved]
title_sort role of the gut microbiome during host ageing [version 1; referees: 2 approved]
publisher F1000 Research Ltd
series F1000Research
issn 2046-1402
publishDate 2018-07-01
description Gut microbial communities participate in key aspects of host biology, including development, nutrient absorption, immunity and disease. During host ageing, intestinal microbes undergo dramatic changes in composition and function and can shift from commensal to pathogenic. However, whether they play a causal role in host ageing and life span has remained an open question for a long time. Recent work in model organisms has revealed for the first time that gut microbes can modulate ageing, opening new questions and opportunities to uncover novel ageing-modulating mechanisms and to design anti-ageing interventions by targeting the gut microbiota.
url https://f1000research.com/articles/7-1086/v1
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AT darioriccardovalenzano roleofthegutmicrobiomeduringhostageingversion1referees2approved
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