TGF-β Mediated Immune Evasion in Cancer—Spotlight on Cancer-Associated Fibroblasts

TGF-β Mediated Immune Evasion in Cancer—Spotlight on Cancer-Associated Fibroblasts

Various components of the tumor microenvironment (TME) play a critical role in promoting tumorigenesis, progression, and metastasis. One of the primary functions of the TME is to stimulate an immunosuppressive environment around the tumor through multiple mechanisms including the activation of the t...

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Bibliographic Details
Main Authors: Parisa Ghahremanifard, Ayan Chanda, Shirin Bonni, Pinaki Bose
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cancers
Subjects:
CAF
TGF-β
tumor immune evasion
immunotherapy
Online Access:https://www.mdpi.com/2072-6694/12/12/3650

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