Isopsoralen ameliorates rheumatoid arthritis by targeting MIF
Abstract Background Isopsoralen (IPRN), one of the active ingredients of Psoralea corylifolia Linn, has anti-inflammatory properties. We attempted to investigate the inhibitory effects of IPRN on rheumatoid arthritis (RA) and characterize its potential mechanism. Methods RA fibroblast-like synoviocy...
Main Authors: | Yi Han, Jinguang Wang, Shufeng Li, Yi Li, Yongli Zhang, Ruojia Zhang, Yuang Zhang, Huancai Fan, Haojun Shi, Jihong Pan, Guanhua Song, Luna Ge, Lin Wang |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2021-09-01
|
Series: | Arthritis Research & Therapy |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13075-021-02619-3 |
Similar Items
-
Isopsoralen Enhanced Osteogenesis by Targeting AhR/ERα
by: Luna Ge, et al.
Published: (2018-10-01) -
Synthesis and anti-rheumatoid arthritis activities of 3-(4-aminophenyl)-coumarin derivatives
by: Yuhang Miao, et al.
Published: (2021-01-01) -
Long-Term Exposure of Psoralen and Isopsoralen Induced Hepatotoxicity and Serum Metabolites Profiles Changes in Female Rats
by: Yingli Yu, et al.
Published: (2019-11-01) -
METTL3 Promotes Activation and Inflammation of FLSs Through the NF-κB Signaling Pathway in Rheumatoid Arthritis
by: Wen Shi, et al.
Published: (2021-07-01) -
A Novel Phytochemical, DIM, Inhibits Proliferation, Migration, Invasion and TNF-α Induced Inflammatory Cytokine Production of Synovial Fibroblasts From Rheumatoid Arthritis Patients by Targeting MAPK and AKT/mTOR Signal Pathway
by: Hongyan Du, et al.
Published: (2019-07-01)