Testicular Cancer Presenting as Gastric Variceal Hemorrhage

Testicular cancer is the most common solid malignancy affecting males between the ages of 15 and 35. The symptomatology caused by this tumor varies according to the site of metastasis. We present the case of a 26-year-old male who arrived to the emergency department with hematemesis. He had no previ...

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Main Authors: Carlos Eduardo Salazar-Mejía, David Hernández-Barajas, Edio Llerena-Hernández, José Luis González-Vela, María Inés Contreras-Salcido, Adriana González-Gutiérrez, Omar David Borjas-Almaguer, Luis Alberto Pérez-Arredondo, Blanca Otilia Wimer-Castillo
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Case Reports in Gastrointestinal Medicine
Online Access:http://dx.doi.org/10.1155/2017/4510387
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spelling doaj-d929f4aa411544f7be2696bfc0db4ed92020-11-24T22:38:02ZengHindawi LimitedCase Reports in Gastrointestinal Medicine2090-65282090-65362017-01-01201710.1155/2017/45103874510387Testicular Cancer Presenting as Gastric Variceal HemorrhageCarlos Eduardo Salazar-Mejía0David Hernández-Barajas1Edio Llerena-Hernández2José Luis González-Vela3María Inés Contreras-Salcido4Adriana González-Gutiérrez5Omar David Borjas-Almaguer6Luis Alberto Pérez-Arredondo7Blanca Otilia Wimer-Castillo8Department of Internal Medicine, University Hospital “Dr. José Eleuterio González” and Faculty of Medicine, Universidad Autónoma de Nuevo León, Monterrey, NL, MexicoOncology Service and Department of Internal Medicine, University Hospital “Dr. José Eleuterio González” and Faculty of Medicine, Universidad Autónoma de Nuevo León, Monterrey, NL, MexicoOncology Service and Department of Internal Medicine, University Hospital “Dr. José Eleuterio González” and Faculty of Medicine, Universidad Autónoma de Nuevo León, Monterrey, NL, MexicoOncology Service and Department of Internal Medicine, University Hospital “Dr. José Eleuterio González” and Faculty of Medicine, Universidad Autónoma de Nuevo León, Monterrey, NL, MexicoOncology Service and Department of Internal Medicine, University Hospital “Dr. José Eleuterio González” and Faculty of Medicine, Universidad Autónoma de Nuevo León, Monterrey, NL, MexicoDepartment of Internal Medicine, University Hospital “Dr. José Eleuterio González” and Faculty of Medicine, Universidad Autónoma de Nuevo León, Monterrey, NL, MexicoGastroenterology Service and Department of Internal Medicine, University Hospital “Dr. José Eleuterio González” and Faculty of Medicine, Universidad Autónoma de Nuevo León, Monterrey, NL, MexicoDepartment of Internal Medicine, University Hospital “Dr. José Eleuterio González” and Faculty of Medicine, Universidad Autónoma de Nuevo León, Monterrey, NL, MexicoDepartment of Internal Medicine, University Hospital “Dr. José Eleuterio González” and Faculty of Medicine, Universidad Autónoma de Nuevo León, Monterrey, NL, MexicoTesticular cancer is the most common solid malignancy affecting males between the ages of 15 and 35. The symptomatology caused by this tumor varies according to the site of metastasis. We present the case of a 26-year-old male who arrived to the emergency department with hematemesis. He had no previous medical history. On arrival, we noted enlargement of the left scrotal sac. There was also a mass in the left scrotum which provoked displacement of the penis and right testis. The serum alpha-fetoprotein level was 17,090 ng/mL, lactate dehydrogenase was 1480 U/L, and human chorionic gonadotropin was 287.4 IU/mL. Upper endoscopy revealed a type 1 isolated gastric varix, treated with cyanoacrylate. A CT scan showed extrinsic compression of the portal vein by lymphadenopathy along with splenic vein partial thrombosis, which caused left-sided portal hypertension. Neoadjuvant chemotherapy was started with etoposide and cisplatin, and seven days later the patient underwent left radical orchiectomy. A postoperative biopsy revealed a pure testicular teratoma. Noncirrhotic left portal hypertension with bleeding from an isolated gastric varix secondary to metastasic testicular cancer has not been described before. Clinicians must consider the possibility of malignancy in the differential diagnosis of a young man presenting with unexplained gastrointestinal bleeding.http://dx.doi.org/10.1155/2017/4510387
collection DOAJ
language English
format Article
sources DOAJ
author Carlos Eduardo Salazar-Mejía
David Hernández-Barajas
Edio Llerena-Hernández
José Luis González-Vela
María Inés Contreras-Salcido
Adriana González-Gutiérrez
Omar David Borjas-Almaguer
Luis Alberto Pérez-Arredondo
Blanca Otilia Wimer-Castillo
spellingShingle Carlos Eduardo Salazar-Mejía
David Hernández-Barajas
Edio Llerena-Hernández
José Luis González-Vela
María Inés Contreras-Salcido
Adriana González-Gutiérrez
Omar David Borjas-Almaguer
Luis Alberto Pérez-Arredondo
Blanca Otilia Wimer-Castillo
Testicular Cancer Presenting as Gastric Variceal Hemorrhage
Case Reports in Gastrointestinal Medicine
author_facet Carlos Eduardo Salazar-Mejía
David Hernández-Barajas
Edio Llerena-Hernández
José Luis González-Vela
María Inés Contreras-Salcido
Adriana González-Gutiérrez
Omar David Borjas-Almaguer
Luis Alberto Pérez-Arredondo
Blanca Otilia Wimer-Castillo
author_sort Carlos Eduardo Salazar-Mejía
title Testicular Cancer Presenting as Gastric Variceal Hemorrhage
title_short Testicular Cancer Presenting as Gastric Variceal Hemorrhage
title_full Testicular Cancer Presenting as Gastric Variceal Hemorrhage
title_fullStr Testicular Cancer Presenting as Gastric Variceal Hemorrhage
title_full_unstemmed Testicular Cancer Presenting as Gastric Variceal Hemorrhage
title_sort testicular cancer presenting as gastric variceal hemorrhage
publisher Hindawi Limited
series Case Reports in Gastrointestinal Medicine
issn 2090-6528
2090-6536
publishDate 2017-01-01
description Testicular cancer is the most common solid malignancy affecting males between the ages of 15 and 35. The symptomatology caused by this tumor varies according to the site of metastasis. We present the case of a 26-year-old male who arrived to the emergency department with hematemesis. He had no previous medical history. On arrival, we noted enlargement of the left scrotal sac. There was also a mass in the left scrotum which provoked displacement of the penis and right testis. The serum alpha-fetoprotein level was 17,090 ng/mL, lactate dehydrogenase was 1480 U/L, and human chorionic gonadotropin was 287.4 IU/mL. Upper endoscopy revealed a type 1 isolated gastric varix, treated with cyanoacrylate. A CT scan showed extrinsic compression of the portal vein by lymphadenopathy along with splenic vein partial thrombosis, which caused left-sided portal hypertension. Neoadjuvant chemotherapy was started with etoposide and cisplatin, and seven days later the patient underwent left radical orchiectomy. A postoperative biopsy revealed a pure testicular teratoma. Noncirrhotic left portal hypertension with bleeding from an isolated gastric varix secondary to metastasic testicular cancer has not been described before. Clinicians must consider the possibility of malignancy in the differential diagnosis of a young man presenting with unexplained gastrointestinal bleeding.
url http://dx.doi.org/10.1155/2017/4510387
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