Characterization of clinical and therapeutic variables in patients with clear cell renal cell adenocarcinoma

• Main Authors: Isora Magdalena Sánchez-Lorenzo, Julio Enrique Torres-Reyes, Leandro Espinosa-Rondón, Isora Magdalena Alvares-Sánchez, Héctor Peña-Rodríguez
• Format: Article
• Language: Spanish
• Published: Universidad de Ciencias Médicas de Las Tunas 2018-05-01
• Series: Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta
• Subjects: carcinoma, renal cell; hematuria; nephrectomy; low back pain
• Online Access: http://revzoilomarinello.sld.cu/index.php/zmv/article/view/1459

<p><strong>Background</strong>: renal cancer has a low prevalence but a high aggressiveness, being the clear cell renal cell adenocarcinoma the most frequent type, with unspecific and varied clinical manifestations. <strong></strong></p><p><strong>Objective</strong>: to characterize clinical and therapeutic aspects in patients with clear cell renal cell adenocarcinoma attended to at the “Dr. Ernesto Guevara de la Serna” Hospital of Las Tunas, from January 2012 to December 2017.<strong></strong></p><p><strong>Methods</strong>: an observational, descriptive and cross-sectional study was carried out at the aforementioned hospital and during the period herein declared. The universe was made up of the 57 patients with renal cancer and the study sample included 45 patients with clear cell renal cell adenocarcinoma.<strong></strong></p><p><strong>Results</strong>: the male sex (62,2 %), the white skin (77,7 %) and the urban origin (66,7 %) represented the highest rates. The condition was frequent in the 50 to 65 age group for 53,3 %. Hypertension (55,5 %) and chronic renal failure (26,7 %) were the associated diseases with the highest incidence in those patients. The commonest metastatic site was the renal capsule (24,4 %), followed by the lung (13,3 %). Lumbo-abdominal pain was the main symptom (84,4 %) and represented the diagnostic impression at the moment of admission in 42,3 % of the cases, followed by urinary tract infection (28,9 %). 35,5 % of the patients presented Guyon's triad. Total nephrectomy was performed on 66,6 % of the patients.<strong></strong></p><p><strong>Conclusions</strong>: Lumbo-abdominal pain was the main symptom in the patients with clear cell renal cell adenocarcinoma, with more cases of metastasis in the renal capsule and with total nephrectomy as treatment.<strong></strong></p>