A Requirement for Argonaute 4 in Mammalian Antiviral Defense

Summary: While interferon (IFN) responses are critical for mammalian antiviral defense, induction of antiviral RNA interference (RNAi) is evident. To date, individual functions of the mammalian RNAi and micro RNA (miRNA) effector proteins Argonautes 1–4 (AGO1–AGO4) during virus infection remain unde...

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Bibliographic Details
Main Authors: Fatemeh Adiliaghdam, Megha Basavappa, Tahnee L. Saunders, Dewi Harjanto, John T. Prior, D. Alexander Cronkite, Nina Papavasiliou, Kate L. Jeffrey
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720300309