Voluntary Wheel Running Reverses Deficits in Social Behavior Induced by Chronic Social Defeat Stress in Mice: Involvement of the Dopamine System

Voluntary Wheel Running Reverses Deficits in Social Behavior Induced by Chronic Social Defeat Stress in Mice: Involvement of the Dopamine System

Voluntary exercise has been reported to have a therapeutic effect on many psychiatric disorders and social stress is known to impair social interaction. However, whether voluntary exercise could reverse deficits in social behaviors induced by chronic social defeat stress (CSDS) and the underlying me...

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Bibliographic Details
Main Authors: Jing Zhang, Zhi-xiong He, Li-min Wang, Wei Yuan, Lai-fu Li, Wen-juan Hou, Yang Yang, Qian-qian Guo, Xue-ni Zhang, Wen-qi Cai, Shu-cheng An, Fa-dao Tai
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Neuroscience
Subjects:
voluntary wheel running
chronic social defeat stress
dopamine system
D2 receptors
nucleus accumbens
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00256/full

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