Dynamic Methylation Changes of DNA and H3K4 by RG108 Improve Epigenetic Reprogramming of Somatic Cell Nuclear Transfer Embryos in Pigs

Dynamic Methylation Changes of DNA and H3K4 by RG108 Improve Epigenetic Reprogramming of Somatic Cell Nuclear Transfer Embryos in Pigs

Background/Aims: DNA methylation and histone modifications are essential epigenetic marks that can significantly affect the mammalian somatic cell nuclear transfer (SCNT) embryo development. However, the mechanisms by which the DNA methylation affects the epigenetic reprogramming have not been fully...

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Bibliographic Details
Main Authors: Yanhui Zhai, Zhiren Zhang, Hao Yu, Li Su, Gang Yao, Xiaoling Ma, Qi Li, Xinglan An, Sheng Zhang, Ziyi Li
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-10-01
Series:Cellular Physiology and Biochemistry
Subjects:
Rg108
SCNT embryos
DNA methylation
Epigenetic reprogramming
Pigs
Online Access:https://www.karger.com/Article/FullText/494598

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