Protocadherin 10 alters γ oscillations, amino acid levels, and their coupling; baclofen partially restores these oscillatory deficits

Protocadherin 10 alters γ oscillations, amino acid levels, and their coupling; baclofen partially restores these oscillatory deficits

Approximately one in 45 children have been diagnosed with Autism Spectrum Disorder (ASD), which is characterized by social/communication impairments. Recent studies have linked a subset of familial ASD to mutations in the Protocadherin 10 (Pcdh10) gene. Additionally, Pcdh10's expression pattern...

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Bibliographic Details
Main Authors: Russell G. Port, Christopher Gajewski, Elizabeth Krizman, Holly C. Dow, Shinji Hirano, Edward S. Brodkin, Gregory C. Carlson, Michael B. Robinson, Timothy P.L. Roberts, Steven J. Siegel
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Neurobiology of Disease
Subjects:
GABA
Gamma-band
Baclofen
ASD
Pcdh10
Amino acid
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996117301936

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