Data on IL-6 c.-174 G>C genotype and allele frequencies in patients with coronary heart disease in dependence of cardiovascular outcome

• Main Authors: Stefan Reichert, Axel Schlitt, Ann-Christin Benten, Britt Hofmann, Hans-Günter Schaller, Susanne Schulz
• Format: Article
• Language: English
• Published: Elsevier 2016-09-01
• Series: Data in Brief
• Online Access: http://www.sciencedirect.com/science/article/pii/S2352340916304553
• ISSN: 2352-3409

In this data article we present data on the distribution of alleles and genotypes of the interleukin (IL)-6 c.-174 G>C polymorphism (rs 1800795) in patients with coronary heart disease (CHD) in dependence of the incidence of new cardiovascular events (combined endpoint: myocardial infarction, stroke/TIA, cardiac death, death according to stroke) within three years follow-up. Moreover, we investigated putative associations between individual expression of IL-6 genotypes and IL-6 serum level. This investigation is a subanalysis of the article entitled “The Interleukin 6 c.-174 CC genotype is a predictor for new cardiovascular events in patients with coronary heart disease within three years follow-up“ (ClinicalTrials.gov identifier: NCT01045070) (Reichert et al., 2016) [1]. Keywords: Coronary heart disease, IL-6 serum level, IL-6 polymorphism, New cardiovascular events