Causative Microorganisms and Antibiotics Susceptibilities in Children with Urinary Tract Infection

Generally, treatment of urinary tract infection (UTI) in children is a difficult task, due to development of high resistance against antibiotics. The object of this study is to investigate the greatest causative microorganisms, their susceptibility and resistance to antibiotics in children suffering...

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Bibliographic Details
Main Authors: Thaer M. Al-Baqer, Samar Abdul Raheem Al-Gharrawi, Noor ALHuda A. Saeed
Format: Article
Language:Arabic
Published: Al-Mustansiriyah University 2021-02-01
Series:Mustansiriyah Journal of Science
Online Access:http://mjs.uomustansiriyah.edu.iq/ojs1/index.php/MJS/article/view/948
Description
Summary:Generally, treatment of urinary tract infection (UTI) in children is a difficult task, due to development of high resistance against antibiotics. The object of this study is to investigate the greatest causative microorganisms, their susceptibility and resistance to antibiotics in children suffering from UTI in Baghdad. A total of 810 urine samples were collected from suspected cases of UTI in children patients of ages (1 day to 12 years) of both sexes. Urine specimens were examined by urinalysis and cultured for isolation of microbial agents. In this study, Bacterial growth was obtained in 202 samples (24.39%) out of 810 urine samples. Various pathogenic organisms were isolated, which represented by A) Gram-Negative bacilli include Escherichia coli (41.58%), Enterobacter spp. (13.68%), Proteus Mirabilis (12.78%), Acinetobacter spp. (4.45%), Providencia spp. (4.45%), Pseudomonas aeruginosa (3.46), Klebsiella pneumoniae (2.47%), Citrobacter spp.(0.49%), Salmonella Spp.(0.49%), B) Gram- Positive cocci: Staphylococcus aureus (11.38%), Enterococcus faecalis (1.98%) and Streptococcus agalactiae (1.48%) C) Candida albicans (0.9%).). According to antibiotic susceptibility test, mostly the isolates were resistant to Nalidixic acid (67.05%), cefotaxime (59.40%) and cefepime (50.49%). Mostly Gram-Negative bacilli were responsible for UTI, and maximum recurrent isolated bacteria were Escherichia coli. The isolated bacteria were found to be sensitive to Imipenem, Amikacin, and ciprofloxacin. Therefore, the selection of antibiotic therapy in UTI should depend on the native sensitivity form of the infecting organism.
ISSN:1814-635X
2521-3520