Cognitive behavioral analysis system of psychotherapy reduces loneliness in patients with persistent depressive disorder

• Main Authors: Matthias A. Reinhard, Katharina Zentz, Tabea Nenov-Matt, Barbara B. Barton, Stephanie V. Rek, Stephan Goerigk, Eva-Lotta Brakemeier, Richard Musil, Andrea Jobst, Frank Padberg
• Format: Article
• Language: English
• Published: Elsevier 2021-07-01
• Series: Journal of Affective Disorders Reports
• Subjects: Loneliness; Social isolation; Cognitive behavioral analysis system of psychotherapy; Persistent depressive disorder
• Online Access: http://www.sciencedirect.com/science/article/pii/S2666915321000986

Background: Loneliness is a distressing and prevalent symptom in patients with persistent depressive disorder (PDD) that is associated with depression severity, a history of childhood maltreatment and rejection sensitivity. As loneliness is no primary focus of psychotherapy to date and the Cognitive Behavioral Analysis System of Psychotherapy (CBASP) particularly addresses interpersonal relationships, we investigate the effects of CBASP on loneliness in an open study in inpatients with PDD. Methods: Sixty patients with PDD (DSM-5) underwent a comprehensive 10-weeks inpatient program of CBASP. Loneliness, social network characteristics, and depressive symptoms were assessed before and after treatment. Further, history of childhood maltreatment, peer victimization, and rejection sensitivity were measured at baseline. Results: Loneliness and depressive symptoms significantly and independently decreased, whereas social network characteristics showed no change after 10 weeks of CBASP. Higher levels of loneliness, larger social network size at baseline, and a history of emotional neglect predicted a larger reduction of loneliness, whereas higher levels of rejection sensitivity and depressive symptoms at baseline were associated with an inferior outcome. Limitations: Unspecific factors of the inpatient setting cannot be ruled out and a control group is lacking. Conclusions: After 10 weeks of CBASP, PDD patients reported a reduced burden of loneliness. The study provides first evidence that CBASP, which addresses dysfunctional interpersonal patterns and their origin in childhood maltreatment and peer victimization, could provide valuable techniques for developing mechanism based psychotherapeutic intervention for loneliness.