Altered Lipid Tumor Environment and Its Potential Effects on NKT Cell Function in Tumor Immunity

Altered Lipid Tumor Environment and Its Potential Effects on NKT Cell Function in Tumor Immunity

Natural killer T (NKT) cells are CD1d restricted T cells that mostly recognize lipid antigens. These cells share characteristics with both adaptive and innate immune cells and have multiple immunoregulatory roles. In a manner similar to innate immune cells, they respond quickly to stimuli and secret...

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Bibliographic Details
Main Authors: Shweta Tiwary, Jay A. Berzofsky, Masaki Terabe
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Immunology
Subjects:
lipid metabolism
tumor immunity
natural killer T-cells
antigen presentation
dendritic cells
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02187/full

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