Features of prescriptions of antihypertensive therapy in patients with diabetes mellitus type 2: Theory and Practice

• Main Authors: I. А. Zupanets, Yu. S. Rudyk, O. V. Gerasymenko
• Format: Article
• Language: English
• Published: Zaporozhye State Medical University 2014-12-01
• Series: Zaporožskij Medicinskij Žurnal
• Subjects: Antihypertensive Agents; Diabetes Mellitus Type 2; Hypertension
• Online Access: http://zmj.zsmu.edu.ua/article/view/35643/31885

Frequent association of DM type 2 with hypertension, presence of early complications and progressive course of disease predetermine selection of an individual antihypertensive therapy in this clinical group. Aim of research was to analyze the practical prescription of drugs in patients with concomitant DM type 2. Methods and results.We studied 71 case history (35 with hypertension and 36 with hypertension and DM type 2). It has been found that in patients with only hypertension diuretics were prescribed in 89%, beta-blockers - in 69%, ACE inhibitors - in 57%, ARBs - in 31%, calcium - 14%. In patients with hypertension and DM diuretics were prescribed in 78 % of cases, beta-blockers - 70 %, ACE inhibitors - 47 %, ARB - 50 %, calcium - 25 % of cases. Among diuretics the most often hydrochlorothiazide was prescribed, among beta-blockers mostly selective one were prescribed. Combination therapy was given in 89 % of patients with only hypertension and 94 % with hypertension and DM. Conclusion. Thus, antihypertensive therapy in patients with DM type 2 is generally compliant. Individual therapy optimization is possible with consultation of Clinical pharmacist.