Chemical Investigation and Antimicrobial Activity of Medicinal Plant <i>Toddalia asiatica</i> Lam
Medicinal plants have become important sources of natural products, which have been used in the development of therapeutic agents. Four new coumarins (1-4) have been isolated together with five known metabolites (5-9) from the medicinal plant T. asiatica. The structures of 1-9 were assigned based on...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Universitas Gadjah Mada
2020-07-01
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Series: | Indonesian Journal of Chemistry |
Subjects: | |
Online Access: | https://jurnal.ugm.ac.id/ijc/article/view/46643 |
Summary: | Medicinal plants have become important sources of natural products, which have been used in the development of therapeutic agents. Four new coumarins (1-4) have been isolated together with five known metabolites (5-9) from the medicinal plant T. asiatica. The structures of 1-9 were assigned based on their spectroscopic data. Compounds (1-9) inhibited the growth of the Gram-negative bacteria E. coli and Gram-positive bacteria S. aureus at a concentration of 25 and 50 μg/disc. Compounds (2-4) inhibited the phytopathogenic fungus C. cucurbitarum at 50 μg/disc. |
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ISSN: | 1411-9420 2460-1578 |