Chemical Investigation and Antimicrobial Activity of Medicinal Plant <i>Toddalia asiatica</i> Lam

Medicinal plants have become important sources of natural products, which have been used in the development of therapeutic agents. Four new coumarins (1-4) have been isolated together with five known metabolites (5-9) from the medicinal plant T. asiatica. The structures of 1-9 were assigned based on...

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Bibliographic Details
Main Authors: Wilmar Maarisit, Misran Lawani
Format: Article
Language:English
Published: Universitas Gadjah Mada 2020-07-01
Series:Indonesian Journal of Chemistry
Subjects:
nmr
Online Access:https://jurnal.ugm.ac.id/ijc/article/view/46643
Description
Summary:Medicinal plants have become important sources of natural products, which have been used in the development of therapeutic agents. Four new coumarins (1-4) have been isolated together with five known metabolites (5-9) from the medicinal plant T. asiatica. The structures of 1-9 were assigned based on their spectroscopic data. Compounds (1-9) inhibited the growth of the Gram-negative bacteria E. coli and Gram-positive bacteria S. aureus at a concentration of 25 and 50 μg/disc. Compounds (2-4) inhibited the phytopathogenic fungus C. cucurbitarum at 50 μg/disc.
ISSN:1411-9420
2460-1578