S100A4 in Cancer Metastasis: Wnt Signaling-Driven Interventions for Metastasis Restriction

S100A4 in Cancer Metastasis: Wnt Signaling-Driven Interventions for Metastasis Restriction

The aberrant activity of Wnt signaling is an early step in the transformation of normal intestinal cells to malignant tissue, leading to more aggressive tumors, and eventually metastases. In colorectal cancer (CRC), metastasis accounts for about 90% of patient deaths, representing the most lethal ev...

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Bibliographic Details
Main Authors: Mathias Dahlmann, Dennis Kobelt, Wolfgang Walther, Giridhar Mudduluru, Ulrike Stein
Format: Article
Language:English
Published: MDPI AG 2016-06-01
Series:Cancers
Subjects:
Wnt signaling
colorectal cancer
metastasis
S100A4
intervention
Online Access:http://www.mdpi.com/2072-6694/8/6/59

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