Safety and skin delayed-type hypersensitivity response in vervet monkeys immunized with Leishmania donovani sonicate antigen delivered with adjuvants

Safety and skin delayed-type hypersensitivity response in vervet monkeys immunized with Leishmania donovani sonicate antigen delivered with adjuvants

In this study, we report on the safety and skin delayed-type hypersensitivity (DTH), responses of the Leishmania donovani whole cell sonicate antigen delivered in conjunction with alum-BCG (AlBCG), Montanide ISA 720 (MISA) or Monophosphoryl lipid A (MPLA) in groups of vervet monkeys. Following three...

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Bibliographic Details
Main Authors: Joshua M. Mutiso, John C. Macharia, Evans Taracha, Kellern Wafula, Hitler Rikoi, Michael M. Gicheru
Format: Article
Language:English
Published: Universidade de São Paulo 2012-02-01
Series:Revista do Instituto de Medicina Tropical de São Paulo
Subjects:
Safety
Delayed-type hypersensitivity (DTH)
Vervet monkeys
Leishmania donovani sonicate antigen
Adjuvants
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652012000100007&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652012000100007&lng=en&tlng=en

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