Research progress on the role of type I vesicular glutamate transporter (VGLUT1) in nervous system diseases

Research progress on the role of type I vesicular glutamate transporter (VGLUT1) in nervous system diseases

Abstract Glutamate (Glu) is the predominant excitatory neurotransmitter in the central nervous system (CNS). Glutamatergic transmission is critical for controlling neuronal activity. In presynaptic neurons, Glu is stored in synaptic vesicles and released by stimulation. The homeostasis of glutamater...

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Bibliographic Details
Main Authors: Xianchao Du, Jiashuo Li, Minghui Li, Xinxin Yang, Zhipeng Qi, Bin Xu, Wei Liu, Zhaofa Xu, Yu Deng
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Cell & Bioscience
Subjects:
Glutamate
CNS
PNS
VGLUT1
Nervous system disease
Online Access:http://link.springer.com/article/10.1186/s13578-020-00393-4

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