Intrinsic Oncogenic Function of Intracellular Connexin26 Protein in Head and Neck Squamous Cell Carcinoma Cells

Intrinsic Oncogenic Function of Intracellular Connexin26 Protein in Head and Neck Squamous Cell Carcinoma Cells

It has long been known that the gap junction is down-regulated in many tumours. One of the downregulation mechanisms is the translocation of connexin, a gap junction protein, from cell membrane into cytoplasm, nucleus, or Golgi apparatus. Interestingly, as tumours progress and reinforce their malign...

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Bibliographic Details
Main Authors: Nobuko Iikawa, Yohei Yamamoto, Yohei Kawasaki, Aki Nishijima-Matsunobu, Maya Suzuki, Takechiyo Yamada, Yasufumi Omori
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:International Journal of Molecular Sciences
Subjects:
gap junction
cell-cell communication
connexin26
head and neck squamous cell carcinoma
ER-Golgi retention signal
cancer progression
Online Access:http://www.mdpi.com/1422-0067/19/7/2134

Internet

http://www.mdpi.com/1422-0067/19/7/2134

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