Intersection of pathological tau and microglia at the synapse

Intersection of pathological tau and microglia at the synapse

Abstract Tauopathies are a heterogenous class of diseases characterized by cellular accumulation of aggregated tau and include diseases such as Alzheimer’s disease (AD), progressive supranuclear palsy and chronic traumatic encephalopathy. Tau pathology is strongly linked to neurodegeneration and cli...

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Bibliographic Details
Main Authors: Thomas Vogels, Adriana-Natalia Murgoci, Tomáš Hromádka
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Acta Neuropathologica Communications
Subjects:
Tau pathology
Tau immunotherapy
Microglia
Astrocytes
Synaptic dysfunction
Complement
Online Access:http://link.springer.com/article/10.1186/s40478-019-0754-y

Internet

http://link.springer.com/article/10.1186/s40478-019-0754-y

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