Cerebrospinal fluid and plasma biomarker trajectories with increasing amyloid deposition in Alzheimer's disease

Cerebrospinal fluid and plasma biomarker trajectories with increasing amyloid deposition in Alzheimer's disease

Abstract Failures in Alzheimer's disease (AD) drug trials highlight the need to further explore disease mechanisms and alterations of biomarkers during the development of AD. Using cross‐sectional data from 377 participants in the BioFINDER study, we examined seven cerebrospinal fluid (CSF) and...

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Bibliographic Details
Main Authors: Sebastian Palmqvist, Philip S Insel, Erik Stomrud, Shorena Janelidze, Henrik Zetterberg, Britta Brix, Udo Eichenlaub, Jeffrey L Dage, Xiyun Chai, Kaj Blennow, Niklas Mattsson, Oskar Hansson
Format: Article
Language:English
Published: Wiley 2019-12-01
Series:EMBO Molecular Medicine
Subjects:
Alzheimer disease
amyloid positron emission tomography
cerebrospinal fluid biomarkers
plasma biomarkers
Online Access:https://doi.org/10.15252/emmm.201911170

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