Chromosomal Aberrations Associated with Clonal Evolution and Leukemic Transformation in Fanconi Anemia: Clinical and Biological Implications

Chromosomal Aberrations Associated with Clonal Evolution and Leukemic Transformation in Fanconi Anemia: Clinical and Biological Implications

Fanconi anaemia (FA) is an inherited disease with congenital and developmental abnormalities, bone marrow failure, and extreme risk of leukemic transformation. Bone marrow surveillance is an important part of the clinical management of FA and often reveals cytogenetic aberrations. Here, we review bo...

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Bibliographic Details
Main Authors: Stefan Meyer, Heidemarie Neitzel, Holger Tönnies
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Anemia
Online Access:http://dx.doi.org/10.1155/2012/349837

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