The Receptor for Advanced Glycation Endproducts (RAGE) Contributes to Severe Inflammatory Liver Injury in Mice

The Receptor for Advanced Glycation Endproducts (RAGE) Contributes to Severe Inflammatory Liver Injury in Mice

Background: The receptor for advanced glycation end products (RAGE) is a multiligand receptor involved in a number of processes and disorders. While it is known that RAGE-signaling can contribute to toxic liver damage and fibrosis, its role in acute inflammatory liver injury and septic multiorgan fa...

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Bibliographic Details
Main Authors: Toni Weinhage, Timo Wirth, Paula Schütz, Philipp Becker, Aloys Lueken, Boris V. Skryabin, Helmut Wittkowski, Dirk Foell
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Immunology
Subjects:
RAGE
sepsis
inflammatory liver injury
PAMPs
DAMPs
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01157/full

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https://www.frontiersin.org/article/10.3389/fimmu.2020.01157/full

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